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Panel—Cell Therapy and Constructs: Why Is It Not Yet In Clinical Use? Welcome and Introductions
SIU Academy®. Sievert K. Oct 5, 2018; 232236
Topic: Basics of tissue engineering and stem cells
Disclosure(s): No disclosures required
Prof. Karl-Dietrich Sievert
Prof. Karl-Dietrich Sievert
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Learning Objectives
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Educational Objectives

At the end of this session, the learner will:

I. Describe several currently applied therapeutic modalities that use a tissue-engineered construct.

II. Understand design of implantable tissue-engineered grafts that exhibit characteristics consistent with the physiology and function of the equivalent healthy native tissue.

III. Explore the use of porcine small intestinal submucosa (SIS) and bladder ECM grafts, which have garnered significant attention.

IV. Comprehend how seeded constructs vs. unseeded technology has potential as an application in tissue engineering.

V. Discuss ongoing clinical trials (Urological Disease Clinical Trials) such as:

a. Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora.

b. Multisystem Cell Therapy for Improvement of Urinary Continence

c. Inflammation and Stem Cells

d. Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures
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